Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
Identifieur interne : 006090 ( Main/Exploration ); précédent : 006089; suivant : 006091Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
Auteurs : L. Galluzzi [France] ; I. Vitale [France] ; J M Abrams [États-Unis] ; E S Alnemri [États-Unis] ; E H Baehrecke [États-Unis] ; M V Blagosklonny [États-Unis] ; T M Dawson [États-Unis] ; V L Dawson [États-Unis] ; W S El-Deiry [États-Unis] ; S. Fulda [Allemagne] ; E. Gottlieb [Royaume-Uni] ; D R Green [États-Unis] ; M O Hengartner [Suisse] ; O. Kepp [France] ; R A Knight [Royaume-Uni] ; S. Kumar [Australie] ; S A Lipton [États-Unis] ; X. Lu [Royaume-Uni] ; F. Madeo [Autriche] ; W. Malorni [Italie] ; P. Mehlen [France] ; G. Nu Ez [États-Unis] ; M E Peter [États-Unis] ; M. Piacentini [Italie] ; D C Rubinsztein [Royaume-Uni] ; Y. Shi [République populaire de Chine] ; H-U Simon [Suisse] ; P. Vandenabeele [Belgique] ; E. White [États-Unis] ; J. Yuan [États-Unis] ; B. Zhivotovsky [Suède] ; G. Melino [Italie, Royaume-Uni] ; G. Kroemer [France]Source :
- Cell Death and Differentiation [ 1350-9047 ] ; 2011.
Abstract
In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations for the definition of distinct cell death morphologies and for the appropriate use of cell death-related terminology, including ‘apoptosis', ‘necrosis' and ‘mitotic catastrophe'. In view of the substantial progress in the biochemical and genetic exploration of cell death, time has come to switch from morphological to molecular definitions of cell death modalities. Here we propose a functional classification of cell death subroutines that applies to both
Url:
DOI: 10.1038/cdd.2011.96
PubMed: 21760595
PubMed Central: 3252826
Affiliations:
- Allemagne, Australie, Autriche, Belgique, France, Italie, Royaume-Uni, République populaire de Chine, Suisse, Suède, États-Unis
- Latium
- Rome
Links toward previous steps (curation, corpus...)
- to stream Pmc, to step Corpus: 000145
- to stream Pmc, to step Curation: 000145
- to stream Pmc, to step Checkpoint: 002236
- to stream Ncbi, to step Merge: 000B19
- to stream Ncbi, to step Curation: 000B19
- to stream Ncbi, to step Checkpoint: 000B19
- to stream Main, to step Merge: 006434
- to stream Main, to step Curation: 006090
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012</title><author><name sortKey="Galluzzi, L" sort="Galluzzi, L" uniqKey="Galluzzi L" first="L" last="Galluzzi">L. Galluzzi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vitale, I" sort="Vitale, I" uniqKey="Vitale I" first="I" last="Vitale">I. Vitale</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Abrams, J M" sort="Abrams, J M" uniqKey="Abrams J" first="J M" last="Abrams">J M Abrams</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Cell Biology, UT Southwestern Medical Center</institution>, Dallas, TX 75390,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alnemri, E S" sort="Alnemri, E S" uniqKey="Alnemri E" first="E S" last="Alnemri">E S Alnemri</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Biochemistry and Molecular Biology, Center for Apoptosis Research, Kimmel Cancer Institute, Thomas Jefferson University</institution>, Philadelphia, PA 19107,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baehrecke, E H" sort="Baehrecke, E H" uniqKey="Baehrecke E" first="E H" last="Baehrecke">E H Baehrecke</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Department of Cancer Biology, University of Massachusetts Medical School</institution>, Worcester, MA 01605,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Blagosklonny, M V" sort="Blagosklonny, M V" uniqKey="Blagosklonny M" first="M V" last="Blagosklonny">M V Blagosklonny</name><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Cell Stress Biology, Roswell Park Cancer Institute</institution>, Buffalo, NY 14263,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, T M" sort="Dawson, T M" uniqKey="Dawson T" first="T M" last="Dawson">T M Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine</institution>, Baltimore, MD 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, V L" sort="Dawson, V L" uniqKey="Dawson V" first="V L" last="Dawson">V L Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine</institution>, Baltimore, MD 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="El Deiry, W S" sort="El Deiry, W S" uniqKey="El Deiry W" first="W S" last="El-Deiry">W S El-Deiry</name><affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Cancer Institute Penn State, Hershey Medical Center</institution>, Philadelphia, PA 17033,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fulda, S" sort="Fulda, S" uniqKey="Fulda S" first="S" last="Fulda">S. Fulda</name><affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Institute for Experimental Cancer Research in Pediatrics, Goethe University</institution>, Frankfurt 60528,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gottlieb, E" sort="Gottlieb, E" uniqKey="Gottlieb E" first="E" last="Gottlieb">E. Gottlieb</name><affiliation wicri:level="1"><nlm:aff id="aff11"><institution>The Beatson Institute for Cancer Research</institution>, Glasgow G61 1BD,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Green, D R" sort="Green, D R" uniqKey="Green D" first="D R" last="Green">D R Green</name><affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Immunology, St. Jude Children's Research Hospital</institution>, Memphis, TN 38105,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hengartner, M O" sort="Hengartner, M O" uniqKey="Hengartner M" first="M O" last="Hengartner">M O Hengartner</name><affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Institute of Molecular Life Sciences, University of Zurich</institution>, 8057 Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kepp, O" sort="Kepp, O" uniqKey="Kepp O" first="O" last="Kepp">O. Kepp</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Knight, R A" sort="Knight, R A" uniqKey="Knight R" first="R A" last="Knight">R A Knight</name><affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Institute of Child Health, University College London</institution>, London WC1N 3JH,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumar, S" sort="Kumar, S" uniqKey="Kumar S" first="S" last="Kumar">S. Kumar</name><affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Centre for Cancer Biology, SA Pathology</institution>, Adelaide, South Australia 5000,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Department of Medicine, University of Adelaide</institution>, Adelaide, South Australia 5005,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Sanford-Burnham Medical Research Institute</institution>, San Diego, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Salk Institute for Biological Studies</institution>, , La Jolla, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff19"><institution>The Scripps Research Institute</institution>, La Jolla, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Univerisity of California, San Diego</institution>, La Jolla, CA 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lu, X" sort="Lu, X" uniqKey="Lu X" first="X" last="Lu">X. Lu</name><affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Ludwig Institute for Cancer Research</institution>, Oxford OX3 7DQ,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Madeo, F" sort="Madeo, F" uniqKey="Madeo F" first="F" last="Madeo">F. Madeo</name><affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Institute of Molecular Biosciences, University of Graz</institution>, 8010 Graz,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Malorni, W" sort="Malorni, W" uniqKey="Malorni W" first="W" last="Malorni">W. Malorni</name><affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Department of Therapeutic Research and Medicines Evaluation, Section of Cell Aging and Degeneration, Istituto Superiore di Sanità</institution>, 00161 Rome,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Istituto San Raffaele Sulmona</institution>, 67039 Sulmona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 67039 Sulmona</wicri:regionArea><wicri:noRegion>67039 Sulmona</wicri:noRegion></affiliation></author><author><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><affiliation wicri:level="1"><nlm:aff id="aff25"><institution>Apoptosis, Cancer and Development, CRCL</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff26"><institution>INSERM, U1052</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff27"><institution>CNRS, UMR5286</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Centre Léon Bérard</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nu Ez, G" sort="Nu Ez, G" uniqKey="Nu Ez G" first="G" last="Nu Ez">G. Nu Ez</name><affiliation wicri:level="1"><nlm:aff id="aff29"><institution>University of Michigan Medical School</institution>, Ann Arbor, MI 48109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Peter, M E" sort="Peter, M E" uniqKey="Peter M" first="M E" last="Peter">M E Peter</name><affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Northwestern University Feinberg School of Medicine</institution>, Chicago, IL 60637,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Piacentini, M" sort="Piacentini, M" uniqKey="Piacentini M" first="M" last="Piacentini">M. Piacentini</name><affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Laboratory of Cell Biology, National Institute for Infectious Diseases IRCCS ‘L Spallanzani'</institution>, 00149 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 00149 Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Department of Biology, University of Rome ‘Tor Vergata'</institution>, 00133 Rome,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rubinsztein, D C" sort="Rubinsztein, D C" uniqKey="Rubinsztein D" first="D C" last="Rubinsztein">D C Rubinsztein</name><affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Cambridge Institute for Medical Research</institution>, Cambridge CB2 0XY,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Shi, Y" sort="Shi, Y" uniqKey="Shi Y" first="Y" last="Shi">Y. Shi</name><affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Shanghai Institutes for Biological Sciences</institution>, 200031 Shanghai,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Simon, H U" sort="Simon, H U" uniqKey="Simon H" first="H-U" last="Simon">H-U Simon</name><affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Institute of Pharmacology, University of Bern</institution>, 3010 Bern,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vandenabeele, P" sort="Vandenabeele, P" uniqKey="Vandenabeele P" first="P" last="Vandenabeele">P. Vandenabeele</name><affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Department for Molecular Biology, Gent University</institution>, 9052 Gent,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff37"><institution>Department for Molecular Biomedical Research</institution>, VIB, 9052 Gent,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="White, E" sort="White, E" uniqKey="White E" first="E" last="White">E. White</name><affiliation wicri:level="1"><nlm:aff id="aff38"><institution>The Cancer Institute of New Jersey</institution>, New Brunswick, NJ 08903,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yuan, J" sort="Yuan, J" uniqKey="Yuan J" first="J" last="Yuan">J. Yuan</name><affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Cell Biology, Harvard Medical School</institution>, Boston, MA 02115,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhivotovsky, B" sort="Zhivotovsky, B" uniqKey="Zhivotovsky B" first="B" last="Zhivotovsky">B. Zhivotovsky</name><affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Institute of Environmental Medicine, Division of Toxicology, Karolinska Institutet</institution>, 17177 Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Melino, G" sort="Melino, G" uniqKey="Melino G" first="G" last="Melino">G. Melino</name><affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Biochemical Laboratory IDI-IRCCS, Department of Experimental Medicine, University of Rome ‘Tor Vergata'</institution>, 00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 00133 Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Medical Research Council, Toxicology Unit, Leicester University</institution>, Leicester LE1 9HN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Metabolomics Platform, Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Centre de Recherche des Cordeliers</institution>, 75005 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Pôle de Biologie, Hôpital Européen Georges Pompidou</institution>, AP-HP, 75908 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Université Paris Descartes</institution>, Paris 5, 75270 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">21760595</idno><idno type="pmc">3252826</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3252826</idno><idno type="RBID">PMC:3252826</idno><idno type="doi">10.1038/cdd.2011.96</idno><date when="2011">2011</date><idno type="wicri:Area/Pmc/Corpus">000145</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000145</idno><idno type="wicri:Area/Pmc/Curation">000145</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000145</idno><idno type="wicri:Area/Pmc/Checkpoint">002236</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">002236</idno><idno type="wicri:Area/Ncbi/Merge">000B19</idno><idno type="wicri:Area/Ncbi/Curation">000B19</idno><idno type="wicri:Area/Ncbi/Checkpoint">000B19</idno><idno type="wicri:doubleKey">1350-9047:2011:Galluzzi L:molecular:definitions:of</idno><idno type="wicri:Area/Main/Merge">006434</idno><idno type="wicri:Area/Main/Curation">006090</idno><idno type="wicri:Area/Main/Exploration">006090</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012</title><author><name sortKey="Galluzzi, L" sort="Galluzzi, L" uniqKey="Galluzzi L" first="L" last="Galluzzi">L. Galluzzi</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vitale, I" sort="Vitale, I" uniqKey="Vitale I" first="I" last="Vitale">I. Vitale</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Abrams, J M" sort="Abrams, J M" uniqKey="Abrams J" first="J M" last="Abrams">J M Abrams</name><affiliation wicri:level="1"><nlm:aff id="aff4"><institution>Department of Cell Biology, UT Southwestern Medical Center</institution>, Dallas, TX 75390,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Alnemri, E S" sort="Alnemri, E S" uniqKey="Alnemri E" first="E S" last="Alnemri">E S Alnemri</name><affiliation wicri:level="1"><nlm:aff id="aff5"><institution>Department of Biochemistry and Molecular Biology, Center for Apoptosis Research, Kimmel Cancer Institute, Thomas Jefferson University</institution>, Philadelphia, PA 19107,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Baehrecke, E H" sort="Baehrecke, E H" uniqKey="Baehrecke E" first="E H" last="Baehrecke">E H Baehrecke</name><affiliation wicri:level="1"><nlm:aff id="aff6"><institution>Department of Cancer Biology, University of Massachusetts Medical School</institution>, Worcester, MA 01605,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Blagosklonny, M V" sort="Blagosklonny, M V" uniqKey="Blagosklonny M" first="M V" last="Blagosklonny">M V Blagosklonny</name><affiliation wicri:level="1"><nlm:aff id="aff7"><institution>Department of Cell Stress Biology, Roswell Park Cancer Institute</institution>, Buffalo, NY 14263,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, T M" sort="Dawson, T M" uniqKey="Dawson T" first="T M" last="Dawson">T M Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine</institution>, Baltimore, MD 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Dawson, V L" sort="Dawson, V L" uniqKey="Dawson V" first="V L" last="Dawson">V L Dawson</name><affiliation wicri:level="1"><nlm:aff id="aff8"><institution>Neuroregeneration and Stem Cell Programs, Institute for Cell Engineering, Johns Hopkins University School of Medicine</institution>, Baltimore, MD 21205,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="El Deiry, W S" sort="El Deiry, W S" uniqKey="El Deiry W" first="W S" last="El-Deiry">W S El-Deiry</name><affiliation wicri:level="1"><nlm:aff id="aff9"><institution>Cancer Institute Penn State, Hershey Medical Center</institution>, Philadelphia, PA 17033,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Fulda, S" sort="Fulda, S" uniqKey="Fulda S" first="S" last="Fulda">S. Fulda</name><affiliation wicri:level="1"><nlm:aff id="aff10"><institution>Institute for Experimental Cancer Research in Pediatrics, Goethe University</institution>, Frankfurt 60528,<country>Germany</country></nlm:aff><country xml:lang="fr">Allemagne</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Gottlieb, E" sort="Gottlieb, E" uniqKey="Gottlieb E" first="E" last="Gottlieb">E. Gottlieb</name><affiliation wicri:level="1"><nlm:aff id="aff11"><institution>The Beatson Institute for Cancer Research</institution>, Glasgow G61 1BD,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Green, D R" sort="Green, D R" uniqKey="Green D" first="D R" last="Green">D R Green</name><affiliation wicri:level="1"><nlm:aff id="aff12"><institution>Department of Immunology, St. Jude Children's Research Hospital</institution>, Memphis, TN 38105,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Hengartner, M O" sort="Hengartner, M O" uniqKey="Hengartner M" first="M O" last="Hengartner">M O Hengartner</name><affiliation wicri:level="1"><nlm:aff id="aff13"><institution>Institute of Molecular Life Sciences, University of Zurich</institution>, 8057 Zurich,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kepp, O" sort="Kepp, O" uniqKey="Kepp O" first="O" last="Kepp">O. Kepp</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff2"><institution>Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff3"><institution>Université Paris Sud-XI</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Knight, R A" sort="Knight, R A" uniqKey="Knight R" first="R A" last="Knight">R A Knight</name><affiliation wicri:level="1"><nlm:aff id="aff14"><institution>Institute of Child Health, University College London</institution>, London WC1N 3JH,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kumar, S" sort="Kumar, S" uniqKey="Kumar S" first="S" last="Kumar">S. Kumar</name><affiliation wicri:level="1"><nlm:aff id="aff15"><institution>Centre for Cancer Biology, SA Pathology</institution>, Adelaide, South Australia 5000,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff16"><institution>Department of Medicine, University of Adelaide</institution>, Adelaide, South Australia 5005,<country>Australia</country></nlm:aff><country xml:lang="fr">Australie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><affiliation wicri:level="1"><nlm:aff id="aff17"><institution>Sanford-Burnham Medical Research Institute</institution>, San Diego, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff18"><institution>Salk Institute for Biological Studies</institution>, , La Jolla, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff19"><institution>The Scripps Research Institute</institution>, La Jolla, CA 92037,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff20"><institution>Univerisity of California, San Diego</institution>, La Jolla, CA 92093,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Lu, X" sort="Lu, X" uniqKey="Lu X" first="X" last="Lu">X. Lu</name><affiliation wicri:level="1"><nlm:aff id="aff21"><institution>Ludwig Institute for Cancer Research</institution>, Oxford OX3 7DQ,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Madeo, F" sort="Madeo, F" uniqKey="Madeo F" first="F" last="Madeo">F. Madeo</name><affiliation wicri:level="1"><nlm:aff id="aff22"><institution>Institute of Molecular Biosciences, University of Graz</institution>, 8010 Graz,<country>Austria</country></nlm:aff><country xml:lang="fr">Autriche</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Malorni, W" sort="Malorni, W" uniqKey="Malorni W" first="W" last="Malorni">W. Malorni</name><affiliation wicri:level="1"><nlm:aff id="aff23"><institution>Department of Therapeutic Research and Medicines Evaluation, Section of Cell Aging and Degeneration, Istituto Superiore di Sanità</institution>, 00161 Rome,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff24"><institution>Istituto San Raffaele Sulmona</institution>, 67039 Sulmona, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 67039 Sulmona</wicri:regionArea><wicri:noRegion>67039 Sulmona</wicri:noRegion></affiliation></author><author><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><affiliation wicri:level="1"><nlm:aff id="aff25"><institution>Apoptosis, Cancer and Development, CRCL</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff26"><institution>INSERM, U1052</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff27"><institution>CNRS, UMR5286</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff28"><institution>Centre Léon Bérard</institution>, 69008 Lyon,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Nu Ez, G" sort="Nu Ez, G" uniqKey="Nu Ez G" first="G" last="Nu Ez">G. Nu Ez</name><affiliation wicri:level="1"><nlm:aff id="aff29"><institution>University of Michigan Medical School</institution>, Ann Arbor, MI 48109,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Peter, M E" sort="Peter, M E" uniqKey="Peter M" first="M E" last="Peter">M E Peter</name><affiliation wicri:level="1"><nlm:aff id="aff30"><institution>Northwestern University Feinberg School of Medicine</institution>, Chicago, IL 60637,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Piacentini, M" sort="Piacentini, M" uniqKey="Piacentini M" first="M" last="Piacentini">M. Piacentini</name><affiliation wicri:level="1"><nlm:aff id="aff31"><institution>Laboratory of Cell Biology, National Institute for Infectious Diseases IRCCS ‘L Spallanzani'</institution>, 00149 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 00149 Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff32"><institution>Department of Biology, University of Rome ‘Tor Vergata'</institution>, 00133 Rome,<country>Italy</country></nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Rubinsztein, D C" sort="Rubinsztein, D C" uniqKey="Rubinsztein D" first="D C" last="Rubinsztein">D C Rubinsztein</name><affiliation wicri:level="1"><nlm:aff id="aff33"><institution>Cambridge Institute for Medical Research</institution>, Cambridge CB2 0XY,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Shi, Y" sort="Shi, Y" uniqKey="Shi Y" first="Y" last="Shi">Y. Shi</name><affiliation wicri:level="1"><nlm:aff id="aff34"><institution>Shanghai Institutes for Biological Sciences</institution>, 200031 Shanghai,<country>China</country></nlm:aff><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Simon, H U" sort="Simon, H U" uniqKey="Simon H" first="H-U" last="Simon">H-U Simon</name><affiliation wicri:level="1"><nlm:aff id="aff35"><institution>Institute of Pharmacology, University of Bern</institution>, 3010 Bern,<country>Switzerland</country></nlm:aff><country xml:lang="fr">Suisse</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Vandenabeele, P" sort="Vandenabeele, P" uniqKey="Vandenabeele P" first="P" last="Vandenabeele">P. Vandenabeele</name><affiliation wicri:level="1"><nlm:aff id="aff36"><institution>Department for Molecular Biology, Gent University</institution>, 9052 Gent,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff37"><institution>Department for Molecular Biomedical Research</institution>, VIB, 9052 Gent,<country>Belgium</country></nlm:aff><country xml:lang="fr">Belgique</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="White, E" sort="White, E" uniqKey="White E" first="E" last="White">E. White</name><affiliation wicri:level="1"><nlm:aff id="aff38"><institution>The Cancer Institute of New Jersey</institution>, New Brunswick, NJ 08903,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Yuan, J" sort="Yuan, J" uniqKey="Yuan J" first="J" last="Yuan">J. Yuan</name><affiliation wicri:level="1"><nlm:aff id="aff39"><institution>Department of Cell Biology, Harvard Medical School</institution>, Boston, MA 02115,<country>USA</country></nlm:aff><country xml:lang="fr">États-Unis</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Zhivotovsky, B" sort="Zhivotovsky, B" uniqKey="Zhivotovsky B" first="B" last="Zhivotovsky">B. Zhivotovsky</name><affiliation wicri:level="1"><nlm:aff id="aff40"><institution>Institute of Environmental Medicine, Division of Toxicology, Karolinska Institutet</institution>, 17177 Stockholm,<country>Sweden</country></nlm:aff><country xml:lang="fr">Suède</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Melino, G" sort="Melino, G" uniqKey="Melino G" first="G" last="Melino">G. Melino</name><affiliation wicri:level="1"><nlm:aff id="aff41"><institution>Biochemical Laboratory IDI-IRCCS, Department of Experimental Medicine, University of Rome ‘Tor Vergata'</institution>, 00133 Rome, Italy</nlm:aff><country xml:lang="fr">Italie</country><wicri:regionArea>, 00133 Rome</wicri:regionArea><placeName><settlement type="city">Rome</settlement><region nuts="2">Latium</region></placeName></affiliation><affiliation wicri:level="1"><nlm:aff id="aff42"><institution>Medical Research Council, Toxicology Unit, Leicester University</institution>, Leicester LE1 9HN,<country>UK</country></nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author><author><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><affiliation wicri:level="1"><nlm:aff id="aff1"><institution>INSERM U848, ‘Apoptosis, Cancer and Immunity'</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff43"><institution>Metabolomics Platform, Institut Gustave Roussy</institution>, 94805 Villejuif,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff44"><institution>Centre de Recherche des Cordeliers</institution>, 75005 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff45"><institution>Pôle de Biologie, Hôpital Européen Georges Pompidou</institution>, AP-HP, 75908 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation><affiliation wicri:level="1"><nlm:aff id="aff46"><institution>Université Paris Descartes</institution>, Paris 5, 75270 Paris,<country>France</country></nlm:aff><country xml:lang="fr">France</country><wicri:regionArea># see nlm:aff country strict</wicri:regionArea></affiliation></author></analytic><series><title level="j">Cell Death and Differentiation</title><idno type="ISSN">1350-9047</idno><idno type="eISSN">1476-5403</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>In 2009, the Nomenclature Committee on Cell Death (NCCD) proposed a set of recommendations for the definition of distinct cell death morphologies and for the appropriate use of cell death-related terminology, including ‘apoptosis', ‘necrosis' and ‘mitotic catastrophe'. In view of the substantial progress in the biochemical and genetic exploration of cell death, time has come to switch from morphological to molecular definitions of cell death modalities. Here we propose a functional classification of cell death subroutines that applies to both <italic>in vitro</italic> and <italic>in vivo</italic> settings and includes extrinsic apoptosis, caspase-dependent or -independent intrinsic apoptosis, regulated necrosis, autophagic cell death and mitotic catastrophe. Moreover, we discuss the utility of expressions indicating additional cell death modalities. On the basis of the new, revised NCCD classification, cell death subroutines are defined by a series of precise, measurable biochemical features.</p></div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Autriche</li><li>Belgique</li><li>France</li><li>Italie</li><li>Royaume-Uni</li><li>République populaire de Chine</li><li>Suisse</li><li>Suède</li><li>États-Unis</li></country><region><li>Latium</li></region><settlement><li>Rome</li></settlement></list><tree><country name="France"><noRegion><name sortKey="Galluzzi, L" sort="Galluzzi, L" uniqKey="Galluzzi L" first="L" last="Galluzzi">L. Galluzzi</name></noRegion><name sortKey="Galluzzi, L" sort="Galluzzi, L" uniqKey="Galluzzi L" first="L" last="Galluzzi">L. Galluzzi</name><name sortKey="Galluzzi, L" sort="Galluzzi, L" uniqKey="Galluzzi L" first="L" last="Galluzzi">L. Galluzzi</name><name sortKey="Kepp, O" sort="Kepp, O" uniqKey="Kepp O" first="O" last="Kepp">O. Kepp</name><name sortKey="Kepp, O" sort="Kepp, O" uniqKey="Kepp O" first="O" last="Kepp">O. Kepp</name><name sortKey="Kepp, O" sort="Kepp, O" uniqKey="Kepp O" first="O" last="Kepp">O. Kepp</name><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><name sortKey="Kroemer, G" sort="Kroemer, G" uniqKey="Kroemer G" first="G" last="Kroemer">G. Kroemer</name><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><name sortKey="Mehlen, P" sort="Mehlen, P" uniqKey="Mehlen P" first="P" last="Mehlen">P. Mehlen</name><name sortKey="Vitale, I" sort="Vitale, I" uniqKey="Vitale I" first="I" last="Vitale">I. Vitale</name><name sortKey="Vitale, I" sort="Vitale, I" uniqKey="Vitale I" first="I" last="Vitale">I. Vitale</name><name sortKey="Vitale, I" sort="Vitale, I" uniqKey="Vitale I" first="I" last="Vitale">I. Vitale</name></country><country name="États-Unis"><noRegion><name sortKey="Abrams, J M" sort="Abrams, J M" uniqKey="Abrams J" first="J M" last="Abrams">J M Abrams</name></noRegion><name sortKey="Alnemri, E S" sort="Alnemri, E S" uniqKey="Alnemri E" first="E S" last="Alnemri">E S Alnemri</name><name sortKey="Baehrecke, E H" sort="Baehrecke, E H" uniqKey="Baehrecke E" first="E H" last="Baehrecke">E H Baehrecke</name><name sortKey="Blagosklonny, M V" sort="Blagosklonny, M V" uniqKey="Blagosklonny M" first="M V" last="Blagosklonny">M V Blagosklonny</name><name sortKey="Dawson, T M" sort="Dawson, T M" uniqKey="Dawson T" first="T M" last="Dawson">T M Dawson</name><name sortKey="Dawson, V L" sort="Dawson, V L" uniqKey="Dawson V" first="V L" last="Dawson">V L Dawson</name><name sortKey="El Deiry, W S" sort="El Deiry, W S" uniqKey="El Deiry W" first="W S" last="El-Deiry">W S El-Deiry</name><name sortKey="Green, D R" sort="Green, D R" uniqKey="Green D" first="D R" last="Green">D R Green</name><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><name sortKey="Lipton, S A" sort="Lipton, S A" uniqKey="Lipton S" first="S A" last="Lipton">S A Lipton</name><name sortKey="Nu Ez, G" sort="Nu Ez, G" uniqKey="Nu Ez G" first="G" last="Nu Ez">G. Nu Ez</name><name sortKey="Peter, M E" sort="Peter, M E" uniqKey="Peter M" first="M E" last="Peter">M E Peter</name><name sortKey="White, E" sort="White, E" uniqKey="White E" first="E" last="White">E. White</name><name sortKey="Yuan, J" sort="Yuan, J" uniqKey="Yuan J" first="J" last="Yuan">J. Yuan</name></country><country name="Allemagne"><noRegion><name sortKey="Fulda, S" sort="Fulda, S" uniqKey="Fulda S" first="S" last="Fulda">S. Fulda</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Gottlieb, E" sort="Gottlieb, E" uniqKey="Gottlieb E" first="E" last="Gottlieb">E. Gottlieb</name></noRegion><name sortKey="Knight, R A" sort="Knight, R A" uniqKey="Knight R" first="R A" last="Knight">R A Knight</name><name sortKey="Lu, X" sort="Lu, X" uniqKey="Lu X" first="X" last="Lu">X. Lu</name><name sortKey="Melino, G" sort="Melino, G" uniqKey="Melino G" first="G" last="Melino">G. Melino</name><name sortKey="Rubinsztein, D C" sort="Rubinsztein, D C" uniqKey="Rubinsztein D" first="D C" last="Rubinsztein">D C Rubinsztein</name></country><country name="Suisse"><noRegion><name sortKey="Hengartner, M O" sort="Hengartner, M O" uniqKey="Hengartner M" first="M O" last="Hengartner">M O Hengartner</name></noRegion><name sortKey="Simon, H U" sort="Simon, H U" uniqKey="Simon H" first="H-U" last="Simon">H-U Simon</name></country><country name="Australie"><noRegion><name sortKey="Kumar, S" sort="Kumar, S" uniqKey="Kumar S" first="S" last="Kumar">S. Kumar</name></noRegion><name sortKey="Kumar, S" sort="Kumar, S" uniqKey="Kumar S" first="S" last="Kumar">S. Kumar</name></country><country name="Autriche"><noRegion><name sortKey="Madeo, F" sort="Madeo, F" uniqKey="Madeo F" first="F" last="Madeo">F. Madeo</name></noRegion></country><country name="Italie"><noRegion><name sortKey="Malorni, W" sort="Malorni, W" uniqKey="Malorni W" first="W" last="Malorni">W. Malorni</name></noRegion><name sortKey="Malorni, W" sort="Malorni, W" uniqKey="Malorni W" first="W" last="Malorni">W. Malorni</name><name sortKey="Melino, G" sort="Melino, G" uniqKey="Melino G" first="G" last="Melino">G. Melino</name><name sortKey="Piacentini, M" sort="Piacentini, M" uniqKey="Piacentini M" first="M" last="Piacentini">M. Piacentini</name><name sortKey="Piacentini, M" sort="Piacentini, M" uniqKey="Piacentini M" first="M" last="Piacentini">M. Piacentini</name></country><country name="République populaire de Chine"><noRegion><name sortKey="Shi, Y" sort="Shi, Y" uniqKey="Shi Y" first="Y" last="Shi">Y. Shi</name></noRegion></country><country name="Belgique"><noRegion><name sortKey="Vandenabeele, P" sort="Vandenabeele, P" uniqKey="Vandenabeele P" first="P" last="Vandenabeele">P. Vandenabeele</name></noRegion><name sortKey="Vandenabeele, P" sort="Vandenabeele, P" uniqKey="Vandenabeele P" first="P" last="Vandenabeele">P. Vandenabeele</name></country><country name="Suède"><noRegion><name sortKey="Zhivotovsky, B" sort="Zhivotovsky, B" uniqKey="Zhivotovsky B" first="B" last="Zhivotovsky">B. Zhivotovsky</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Asie/explor/AustralieFrV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006090 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 006090 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Asie
|area= AustralieFrV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= PMC:3252826
|texte= Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
}}
Pour générer des pages wiki
HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i -Sk "pubmed:21760595" \
| HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd \
| NlmPubMed2Wicri -a AustralieFrV1
| This area was generated with Dilib version V0.6.33. |  |